Moving on from the classical
HPTLC systems used for research, CAMAG has developed the new fully automated
HPTLC PRO system for hassle-free testing of multiple samples. The HPTLC PRO
system is a patented technology which is best suited for routine Quality Control
analytes extracted from complex matrices, providing reproducible and reliable
results. The HPTLC PRO system can at a single time
support 75 samples, up to 5 plates, and up to three independent developing
solvents without intervention. It can also support derivatization, MS coupling,
and plate storage. It is the first fully automated HPTLC system worldwide.
The system has the following
- Application: The
application module has a capacity of 75 vials designed for autonomous
application of multiple samples on 5 different plates. The plate storage
module is attached to the application module which directly gets the
plates. This can support the application of more than 200 samples per day
on 20X10 glass plates. To ensure highly precise application of samples as
narrow bands, the module has a laser-controlled application of samples
with an optimal spraying distance. The needle distance and dosage speed
will vary depending on the sample and solvent used. In order to avoid
cross-contamination, the syringe generates a highly effective separation
bubble between the rinsing solvent and the sample solution; the syringe is also cleaned after each application. The
Application module can be used as a stand-alone system or as a part of the
HPTLC PRO module. In case there are two or more modules connected, the
plate moves via a conveyer belt from one module to another.
- Development: The
development step is a very crucial step in the HPTLC analysis. Parameters such as the chamber selected and its
configuration determine the separation and ability to reproduce the
chromatography, the gas phase also significantly affects the separation.
The aim of the automatic chamber i.e. CAMAG HPTLC PRO Module Development
is to make sure the development is more reproducible and independent of
human interaction. In the automatic chamber, the activity if the
stationary phase can be adjusted, and the gas phase can also be actively
circulated during development to have an effect on the separation of the
Plate Storage: The plate storage can hold two portable stackers for
five clean and five processed HPTLC glass plates.
Software: CAMAG visionCATS software supports the HPTLC PRO Analysis
and manages all the data modules.
We at Anchrom have the HPTLC PRO
Application & Development module at our India specific HPTLC Application
center in Mumbai, becoming the world’s first dealer to install this instrument
except for CAMAG.
The next modules of the CAMAG
HPTLC PRO system is as follows:
Expected launch in 2021
launch in 2022
launch in 2022